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Marie-Claude Fournié-Zaluski Selected Research

PL265

1/2017Synergistic combinations of the dual enkephalinase inhibitor PL265 given orally with various analgesic compounds acting on different targets, in a murine model of cancer-induced bone pain.
10/2016Preventive and alleviative effects of the dual enkephalinase inhibitor (Denki) PL265 in a murine model of neuropathic pain.
3/2015Long-lasting oral analgesic effects of N-protected aminophosphinic dual ENKephalinase inhibitors (DENKIs) in peripherally controlled pain.

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Marie-Claude Fournié-Zaluski Research Topics

Disease

7Pain (Aches)
01/2017 - 07/2003
4Hyperalgesia
01/2017 - 10/2008
4Neuralgia (Stump Neuralgia)
10/2016 - 04/2012
3Neoplasms (Cancer)
01/2017 - 02/2004
2Osteosarcoma (Osteogenic Sarcoma)
11/2009 - 10/2008
2Paralysis (Palsy)
07/2009 - 10/2003
1Cancer Pain
01/2017
1Acute Pain
10/2016
1Chronic Pain
10/2016
1Fibrosarcoma
11/2009
1Neoplastic Processes
11/2009
1Alzheimer Disease (Alzheimer's Disease)
04/2009
1Pathologic Processes
02/2004
1Botulism
10/2003
1Insulin Resistance
02/2003

Drug/Important Bio-Agent (IBA)

9Neprilysin (Neutral Endopeptidase)IBA
01/2017 - 02/2003
7EnkephalinsIBA
01/2017 - 11/2009
6Analgesics (Analgesic Drugs)IBA
01/2017 - 07/2003
5Opioid Analgesics (Opioids)IBA
01/2017 - 04/2012
4Opioid Receptors (Opioid Receptor)IBA
01/2017 - 10/2008
3EnzymesIBA
01/2017 - 02/2004
3PL265IBA
01/2017 - 03/2015
3Metalloproteases (Metalloproteinases)IBA
09/2015 - 10/2003
2Morphine (MS Contin)FDA LinkGeneric
01/2017 - 10/2016
2Opiate AlkaloidsIBA
10/2016 - 10/2008
2Leucine EnkephalinIBA
10/2016 - 09/2015
2AminopeptidasesIBA
09/2015 - 03/2015
2Gabapentin (Neurontin)FDA LinkGeneric
03/2015 - 10/2008
2Opioid Peptides (Opioid Peptide)IBA
07/2014 - 04/2012
1Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA
01/2017
1Narcotic Antagonists (Opioid Antagonists)IBA
01/2017
1LigandsIBA
10/2016
1mu Opioid Receptors (mu Opioid Receptor)IBA
10/2016
1delta Opioid Receptors (delta Opioid Receptor)IBA
10/2016
1DisulfidesIBA
09/2015
1Methionine EnkephalinIBA
09/2015
1CD13 Antigens (Alanine Aminopeptidase)IBA
04/2012
1fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
04/2012
1CannabinoidsIBA
04/2012
1A-317491IBA
11/2009
1Proteins (Proteins, Gene)FDA Link
07/2009
1Acetylcholine (Acetylcholine Chloride)FDA Link
07/2009
1Amyloid beta-PeptidesIBA
04/2009
1Peptides (Polypeptides)IBA
04/2009
1cyprodimeIBA
10/2008
1ZincIBA
10/2003
1Neurotransmitter Agents (Neurotransmitter)IBA
10/2003
1mixanprilIBA
02/2003
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
02/2003
1Insulin (Novolin)FDA Link
02/2003

Therapy/Procedure

3Oral Administration
10/2016 - 10/2008
1Ligation
10/2016